Modafinil was originally developed to treat narcolepsy but is increasingly used off-label as a “smart drug” to promote cognitive enhancement. While past studies have found that it improves alertness and concentration in sleep-deprived individuals, less attention has been given to the drug’s effects in healthy non-sleep-disordered individuals.
A new study analyzed resting-state functional magnetic resonance imaging (rs-fMRI) data using Eigenvector Centrality (EC). The analysis showed that modafinil enhances the connectivity of the bilateral primary visual cortex with specific cerebellar and frontal regions.
It’s used to treat narcolepsy
Modafinil Australia Online is a wakefulness-promoting drug that is use to treat excessive sleepiness cause by narcolepsy and shift work sleep disorder. It can also be use to improve concentration and alertness in people who are not sleep-deprive. It may increase the risk of certain side effects, such as gastrointestinal problems and headaches. In addition, it can interact with other drugs, so it’s important to tell your doctor what other medications you are taking.
In two nine-week double-blind studies, 200 mg of modafinil per day significantly improved standard measures of daytime sleepiness in narcolepsy patients. The improvement was sustaine throughout the waking day and was comparable to that seen with other wakefulness-promoting agents, such as methylphenidate and d-amphetamine.
However, the drug’s effect on memory is less clear. Researchers suspect that it could negatively affect brain receptors that consolidate short-term memory and regulate flexibility when responding to diverse stimuli. This is particularly worrying because it might make young people less able to cope with social situations.
It’s use to treat shift work sleep disorder
Shift work sleep disorder (SWSD) is a condition that causes people to suffer from difficulty falling asleep or staying awake at night. This can lead to decreased productivity and may increase the risk of accidents at work. SWSD is cause by a misalignment between your body’s melatonin levels and its internal clock, which results in frequent sleep disruptions. It can also be cause by caffeine use and noise disturbances.
The FDA has approved two medications, modafinil, and Modalert 200 Australia, to treat SWSD. These medications are non-amphetamine stimulants that are often prescribe for narcolepsy.
Before taking this medication, tell your doctor if you are allergic to it or any other drugs. Also, tell your doctor if you have any other medical conditions, especially heart problems, liver disease, high blood pressure, mental/mood disorders, or a history of drug abuse. Avoid drinking alcohol or using marijuana (cannabis) while taking this medicine. These substances can make the side effects worse.
It’s use to treat sleep apnea
Modafinil, also know as Provigil, is a drug use to treat sleep disorders and excessive daytime sleepiness. It’s been show to be an effective and well-tolerated treatment for narcolepsy, shift work sleep disorder, and obstructive sleep apnea. It has also been found to reduce residual daytime sleepiness in patients with obstructive sleep apnea who are using CPAP therapy.
In healthy people, modafinil has been show to increase concentration and improve learning and memory. It also improves something called fluid intelligence, which is our ability to solve problems and think creatively.
In some cases, long-term use of Modafinil can cause serious and life-threatening rashes, including Stevens-Johnson syndrome. It’s important to talk to your doctor about this risk before taking the drug. It’s also important to know that this drug may interact with other medications. This includes over-the-counter and prescription drugs. You should also be aware that Modafinil can become habit-forming if you take it for a prolonged time.
It’s use to treat obstructive sleep apnea
Modafinil is an FDA-approve wakefulness agent that has been demonstrate to reduce excessive daytime sleepiness (EDS) in narcolepsy, obstructive sleep apnea, and idiopathic hype somnolence. It also enhances the effectiveness of CPAP therapy for patients with obstructive sleep apnea. Unlike conventional CNS stimulants, modafinil has no negative effects on motor activity and causes fewer adverse drug reactions.
It is important to note that pharmacologic suppression of EDS is not a primary treatment for obstructive sleep apnea. Instead, if EDS recurs in the setting of optimal CPAP therapy, the cause should be investigate. This may include a mechanical issue (such as mask leakage or an adjustment of CPAP pressure), a change in diet, or noncompliance with CPAP therapy.
Two recent studies11,12 have found that modafinil can improve alertness on the MWT and MSLT and decrease perceptions of EDS. However, the results are modest. These effects are most notable in the elderly, where elimination and metabolism of the drug slowly.